Israel-Palestine: R2P

A domestic issue with international side effects is a global issue.
The current situation governing Israel-Palestine cannot be found merely domestic issues of these parties. The dispute of Israeli and Palestinian states itself has been the origin of a few wars and emergence of militia and terrorist groups in the region, which are threats against all. 
The continues violation of human rights and humanitarian law by third parties like Hamas and Hezbollah under the shade of the dispute is now identified a constant parameter in this regard. Therefore, the world community and the major Arab states have this right to take advantage of all means to settle peace by invoking the principle of Responsibility to Protect. It is evident, the principle would legitimate any essential decision on behalf of Palestinian nation by the world community if the Palestinian state fails to accomplish its part. 
At the end, the model of multilateral negotiation among Israel, West Bank and the GCC is recommended.

Israel-Palestine: "Peace Against Enemies"

Although the Middle East has opened a widespread opportunities for the U.S. but the recent rapid developments in the arena of international relations and technology have raised the necessity for the Washington D.C. to gradually decrease its focus on the region and instead, strongly address the growing issues of Russia, China and new order in the east Asia. Therefore, the Palestine issue as the first and the most significant problem of the Middle East must be resolved. 
Definitely, settlement of the issue would be in favor of all sides including Israel and the major Arab states. Without a doubt, a permanent peace agreement between Tel Aviv and Ramallah could be also considered a geostrategic attack on Tehran. The predictable results of such a deal can put an end to the diplomatic isolation of Israel in the region and change the current balance of power against the Islamic Republic. 
According to historical experience, economic sanctions cannot singly realize a specific objective but also might provoke the rogue state to aggressive reactions. Thus, the Washington D.C. should target  geostrategic interests of Tehran in order to strengthen the functions of the recent sanctions.